SCHEMBL6571013

SCHEMBL6571013

COCCN(CCOC)c1ccc(N)cc1-c1ccc(C)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRHR1 P34998 5/20 0.38
ALDH1A1 P00352 5/20 0.34
NPC1 O15118 3/20 0.34
RAB9A P51151 3/20 0.34
HSD17B10 Q99714 2/20 0.34
TSHR P16473 1/20 0.34
CASP1 P29466 1/20 0.34
CASP7 P55210 1/20 0.34
ACHE P22303 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
LMNA P02545 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
BACE1 P56817 1/20 0.33
HPGD P15428 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
MAPT P10636 2/20 0.32
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6572090 0.93 CRHR1 (0.34) CRHR1ALDH1A1TSHRMEN1KMT2A
SCHEMBL6572015 0.87 TDP1 (0.41) CRHR1ALDH1A1NPC1RAB9AHSD17B10
SCHEMBL6572104 0.87 CRHR1 (0.32) CRHR1
SCHEMBL6574108 0.87 CRHR1 (0.33) CRHR1ALDH1A1ACHEMEN1KMT2A
SCHEMBL6572455 0.87 USP7 (0.35) CRHR1ALDH1A1HSD17B10CASP1MEN1
SCHEMBL6571986 0.87 MEN1 (0.41) CRHR1NPC1RAB9AMEN1KMT2A
SCHEMBL6571975 0.87 GRM2 (0.38) CRHR1ALDH1A1RAB9ASMN1; SMN2
SCHEMBL6572183 0.86 FYN (0.36) CRHR1ALDH1A1MEN1KMT2AHPGD
SCHEMBL6574909 0.86 ALDH1A1 (0.40) CRHR1ALDH1A1NPC1RAB9AHSD17B10
SCHEMBL6573595 0.85 CRHR1 (0.34) CRHR1TSHRMAPTKDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1051143-B1 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES WELLA AG (DE) 2004-07-21 EP claimed
EP-1051143-B1 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES WELLA AG (DE) 2004-07-21 EP disclosed
US-6500213-B1 Oxidizing hair coloring agents containing 2,5-diamino-1-phenylbenzene derivatives and novel 2,5-diamino-1-phenylbenzene derivatives WELLA AKTIENGESELLSCHAFT (DE) 2002-12-31 US disclosed
EP-1051143-A2 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES Wella Aktiengesellschaft (DE) 2000-11-15 EP disclosed
WO-1999059527-A2 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES WELLA AKTIENGESELLSCHAFT (DE) 1999-11-25 WO disclosed