Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.35 |
| ▸ | EPHA4 | P54764 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6574870 | 0.98 | PLA2G7 (0.46) | PLA2G7CASP1ALDH1A1ABL1TSHR | |
| SCHEMBL6576308 | 0.82 | PDE10A (0.55) | PLA2G7CASP1ALDH1A1ABL1TSHR | |
| SCHEMBL21020907 | 0.81 | PLA2G7 (0.47) | PLA2G7CASP1ALDH1A1ABL1TSHR | |
| SCHEMBL7684845 | 0.81 | ALDH1A1 (0.50) | PLA2G7CASP1ALDH1A1TSHRCYP3A4 | |
| Hydrochloric Acid SCHEMBL6780711 | 0.81 | PDE10A (0.53) | PLA2G7CASP1ALDH1A1ABL1TSHR | |
| SCHEMBL30092397 | 0.79 | PLA2G7 (0.65) | PLA2G7CASP1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL31607621 | 0.79 | PLA2G7 (0.65) | PLA2G7CASP1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL29901139 | 0.79 | ALDH1A1 (0.62) | ALDH1A1KEAP1MEN1NPC1KMT2A | |
| SCHEMBL30377758 | 0.79 | NISCH (0.52) | ABL1PDE10ANISCHAGPAT2SLC9A1 | |
| SCHEMBL9139591 | 0.79 | NISCH (0.52) | ABL1PDE10ANISCHAGPAT2SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | claimed |
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | disclosed |