Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6780711 | 0.98 | PDE10A (0.53) | PDE10ACASP1TSHRNPC1PLA2G7 | |
| SCHEMBL6572548 | 0.82 | PDE10A (0.59) | PDE10ACASP1TSHRNPC1PLA2G7 | |
| SCHEMBL6571302 | 0.82 | PLA2G7 (0.47) | PDE10ACASP1TSHRNPC1PLA2G7 | |
| Hydrochloric Acid SCHEMBL6574870 | 0.81 | PLA2G7 (0.46) | PDE10ACASP1TSHRNPC1PLA2G7 | |
| Hydrochloric Acid SCHEMBL6781826 | 0.81 | PDE10A (0.57) | PDE10ACASP1TSHRNPC1PLA2G7 | |
| SCHEMBL21020907 | 0.79 | PLA2G7 (0.47) | PDE10ACASP1TSHRNPC1PLA2G7 | |
| SCHEMBL12327783 | 0.77 | CNR1 (0.47) | NPC1ALDH1A1IDO1NISCHSLC9A1 | |
| SCHEMBL12293450 | 0.77 | ALDH1A1 (0.47) | NPC1ALDH1A1IDO1NISCHCYP2D6 | |
| Ethane SCHEMBL28807032 | 0.77 | PDE10A (0.65) | PDE10ACASP1TSHRNPC1ALDH1A1 | |
| SCHEMBL30880219 | 0.77 | PDE10A (0.64) | PDE10ACASP1TSHRNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208077-B1 | 2-HYDROXY-5-AMINO-BIPHENYL-DERIVATIVES AND OXIDATIVE HAIR COLOURING AGENTS CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2004-04-21 | — | — | EP | disclosed |
| EP-1208077-A1 | 2-HYDROXY-5-AMINO-BIPHENYL-DERIVATIVES AND OXIDATIVE HAIR COLOURING AGENTS CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2002-05-29 | — | — | EP | disclosed |
| WO-2002002507-A1 | 2-HYDROXY-5-AMINO-BIPHENYL-DERIVATIVES AND OXIDATIVE HAIR COLOURING AGENTS CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2002-01-10 | — | — | WO | disclosed |