Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 4/20 | 0.54 |
| ▸ | RARB | P10826 | 4/20 | 0.54 |
| ▸ | RARG | P13631 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.54 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.54 |
| ▸ | GOT1 | P17174 | 1/20 | 0.54 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7786848 | 0.89 | LMNA (0.50) | RARARARBRARGMEN1NR1I2 | |
| SCHEMBL7786948 | 0.89 | RARB (0.44) | RARARARBRARGMEN1NR1I2 | |
| SCHEMBL7047540 | 0.88 | RARB (0.50) | RARARARBRARGMEN1NR1I2 | |
| SCHEMBL3807973 | 0.87 | RARB (0.67) | RARARARBRARGMEN1NR1I2 | |
| SCHEMBL7786877 | 0.84 | RARA (0.49) | RARARARBRARGMEN1NR1I2 | |
| SCHEMBL6535398 | 0.83 | ALOX5 (0.52) | RARARARBRARGMEN1NR1I2 | |
| SCHEMBL7796793 | 0.83 | RARB (0.47) | RARARARBRARGMEN1NR1I2 | |
| SCHEMBL7786898 | 0.83 | PDE4A (0.47) | RARARARBRARGMEN1NR1I2 | |
| SCHEMBL7786850 | 0.81 | NPC1 (0.53) | RARARARBRARGMEN1NR1I2 | |
| SCHEMBL3807977 | 0.81 | RARA (0.67) | RARARARBRARGMEN1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920312-B1 | APOPTOSIS INDUCING ADAMANTYL DERIVATIVES AND THEIR USAGE AS ANTI-CANCER AGENTS | GALDERMA RES & DEV (FR) | 2004-12-08 | — | — | EP | claimed |
| EP-0465343-B1 | Pharmaceutical or cosmetical composition comprising a retinoid and a sterol in association | CIRD GALDERMA (FR) | 1994-06-15 | — | — | EP | claimed |