Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | MYC | P01106 | 1/20 | 0.52 |
| ▸ | MAX | P61244 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696913 | 0.87 | POLB (0.50) | KMT2ATSHRTDP1ALDH1A1MEN1 | |
| SCHEMBL6574685 | 0.84 | LMNA (0.51) | KMT2ATSHRTDP1ALDH1A1MEN1 | |
| SCHEMBL6571992 | 0.82 | PKM (0.52) | KMT2ATSHRTDP1ALDH1A1MEN1 | |
| SCHEMBL126989 | 0.82 | KMT2A (0.70) | KMT2ATSHRTDP1ALDH1A1MEN1 | |
| SCHEMBL29390514 | 0.82 | KMT2A (0.70) | KMT2ATSHRTDP1ALDH1A1MEN1 | |
| SCHEMBL6572033 | 0.81 | MYC (0.48) | KMT2ATSHRTDP1ALDH1A1MEN1 | |
| SCHEMBL29390080 | 0.81 | KMT2A (0.65) | KMT2ATSHRTDP1ALDH1A1MEN1 | |
| SCHEMBL108393 | 0.81 | KMT2A (0.65) | KMT2ATSHRTDP1ALDH1A1MEN1 | |
| SCHEMBL6572192 | 0.81 | HCAR3 (0.49) | KMT2AALDH1A1MEN1MAPTMYC | |
| SCHEMBL18415460 | 0.79 | KMT2A (0.58) | KMT2AALDH1A1MEN1MAPTMYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | disclosed |
| US-6500213-B1 | Oxidizing hair coloring agents containing 2,5-diamino-1-phenylbenzene derivatives and novel 2,5-diamino-1-phenylbenzene derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2002-12-31 | — | — | US | disclosed |