Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | GFER | P55789 | 2/20 | 0.45 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6572473 | 0.98 | RAB9A (0.44) | RAB9AMAPTNPC1GFERSKP2 | |
| SCHEMBL1076315 | 0.91 | SKP2 (0.54) | RAB9AMAPTNPC1SKP2SMN1; SMN2 | |
| SCHEMBL6572099 | 0.90 | HTR2A (0.53) | RAB9AMAPTSKP2SMN1; SMN2HSD17B10 | |
| Hydrochloric Acid SCHEMBL6574359 | 0.90 | SKP2 (0.53) | RAB9AMAPTNPC1SKP2SMN1; SMN2 | |
| SCHEMBL16758692 | 0.88 | HTR2A (0.56) | RAB9AMAPTSKP2SMN1; SMN2HSD17B10 | |
| Hydrochloric Acid SCHEMBL6572967 | 0.88 | HTR2A (0.51) | RAB9AMAPTSKP2SMN1; SMN2HSD17B10 | |
| SCHEMBL6570730 | 0.85 | TAAR1 (0.42) | RAB9AMAPTNPC1SKP2SMN1; SMN2 | |
| SCHEMBL6573221 | 0.84 | CA2 (0.42) | RAB9AMAPTGFERSMN1; SMN2HSD17B10 | |
| Hydrochloric Acid SCHEMBL6573139 | 0.84 | TAAR1 (0.41) | RAB9AMAPTNPC1SKP2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6570694 | 0.82 | CA2 (0.41) | MAPTGFERKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | claimed |
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | disclosed |