Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8107403 | 0.91 | HDAC4 (0.39) | HDAC4HDAC2HDAC8GABRG2GABRB3 | |
| SCHEMBL6570817 | 0.87 | HDAC4 (0.39) | HDAC4HDAC2HDAC8GABRG2GABRB3 | |
| SCHEMBL6570737 | 0.86 | MEN1 (0.47) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL6571296 | 0.86 | GAA (0.40) | ALDH1A1MEN1KMT2AMAPTTHRB | |
| SCHEMBL6571978 | 0.84 | HTR7 (0.41) | MEN1KMT2AMAPTHTR2A | |
| SCHEMBL6571974 | 0.84 | ALDH1A1 (0.42) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL6571940 | 0.83 | ALDH1A1 (0.42) | ALDH1A1CYP19A1KDM4EHPGD | |
| SCHEMBL6570844 | 0.83 | TRIM24 (0.42) | HDAC8ALDH1A1CYP19A1KDM4ENPC1 | |
| SCHEMBL6573059 | 0.82 | HDAC4 (0.40) | HDAC4HDAC2HDAC8ALDH1A1MAPT | |
| SCHEMBL6570775 | 0.81 | ERN1 (0.42) | ALDH1A1MEN1KMT2AMAPTCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | claimed |
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | disclosed |
| US-6500213-B1 | Oxidizing hair coloring agents containing 2,5-diamino-1-phenylbenzene derivatives and novel 2,5-diamino-1-phenylbenzene derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2002-12-31 | — | — | US | disclosed |