Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6570912 | 0.83 | ALDH1A1 (0.36) | HTTCYP3A4ALOX12KMT2AALDH1A1 | |
| SCHEMBL6571461 | 0.83 | CHEK1 (0.41) | PTGDR2 | |
| SCHEMBL6572538 | 0.82 | HTT (0.48) | FNTAFNTBHTTFOLH1CYP3A4 | |
| SCHEMBL6572908 | 0.82 | NPC1 (0.35) | HTTCYP3A4ALOX12KMT2AGAA | |
| Hydrochloric Acid SCHEMBL6572537 | 0.82 | CHEK1 (0.40) | PTGDR2 | |
| SCHEMBL6574529 | 0.81 | PLA2G7 (0.46) | HTTCYP3A4ALOX12KMT2AGAA | |
| SCHEMBL6571001 | 0.81 | LMNA (0.41) | CYP2C9KMT2AGAAMAPK1SMN1; SMN2 | |
| SCHEMBL6574137 | 0.81 | ALOX5AP (0.36) | HTTCYP3A4ALOX12KMT2AALDH1A1 | |
| SCHEMBL6571569 | 0.81 | NPC1 (0.35) | HTTCYP3A4ALOX12KMT2AALDH1A1 | |
| SCHEMBL6571545 | 0.80 | KDM4E (0.42) | FNTAFNTBHTTFOLH1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | claimed |
| US-6500213-B1 | Oxidizing hair coloring agents containing 2,5-diamino-1-phenylbenzene derivatives and novel 2,5-diamino-1-phenylbenzene derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2002-12-31 | — | — | US | disclosed |