Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1586340 | 0.87 | SLC1A3 (0.54) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 | |
| SCHEMBL6576561 | 0.83 | NR4A2 (0.54) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 | |
| SCHEMBL9292657 | 0.83 | CNR1 (0.48) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 | |
| SCHEMBL9291604 | 0.83 | SLC6A2 (0.50) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 | |
| SCHEMBL8747779 | 0.82 | MAOA (0.45) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 | |
| SCHEMBL10584101 | 0.81 | NR4A1 (0.57) | CYP1A2CYP2C19MAOBLMNAPPARG | |
| SCHEMBL5122883 | 0.80 | CNR2 (0.54) | KMT2AMEN1GSK3BBACE1ALDH1A1 | |
| SCHEMBL6573433 | 0.80 | SLC1A3 (0.45) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 | |
| SCHEMBL3920061 | 0.77 | AOC3 (0.44) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 | |
| SCHEMBL10334664 | 0.75 | SLC1A3 (0.46) | SLC1A3SLC1A2SLC1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973537-A4 | COCAETHYLENE IMMUNOGENS AND ANTIBODIES | DRUGABUSE SCIENCES S A S (FR) | 2004-12-01 | — | — | EP | disclosed |
| US-6541004-B1 | Cocaethylene immunogens and antibodies | DRUGABUSE SCIENCES, INC. | 2003-04-01 | — | — | US | disclosed |
| US-20020102659-A1 | Cocaethylene immunogens and antibodies | DRUGABUSE SCIENCES S.A.S. (FR) | 2002-08-01 | — | — | US | disclosed |
| US-6114508-A | 2-CARBOXYETHYL-3-BENZOYLOXY-N-METHYLTROPANE DERIVATIVES; COCAINE DETOXIFICATION; VACCINES | DRUGABUSE SCIENCES, INC. (US) | 2000-09-05 | — | — | US | disclosed |
| EP-0973537-A1 | COCAETHYLENE IMMUNOGENS AND ANTIBODIES | DrugAbuse Sciences S.A.S. (FR) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998042359-A1 | COCAETHYLENE IMMUNOGENS AND ANTIBODIES | DRUG ABUSE SCIENCES, INC. (US) | 1998-10-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020102659-A1 | Cocaethylene immunogens and antibodies | CES2, BCHE, ERP44 | SLC1A3 553/4885SLC1A2 510/4885SLC1A1 454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.