Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 11/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | QPCT | Q16769 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5718502 | 0.91 | MAPT (0.43) | ALDH1A1SMN1; SMN2GLAMAPTKDM4E | |
| SCHEMBL6571775 | 0.84 | POLB (0.42) | ALDH1A1SMN1; SMN2MAPTKDM4EKMT2A | |
| SCHEMBL6571751 | 0.82 | MAPT (0.46) | ALDH1A1SMN1; SMN2MAPTKDM4EKMT2A | |
| SCHEMBL6570543 | 0.82 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL8020996 | 0.81 | MAPT (0.46) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL6151236 | 0.81 | MAPT (0.41) | ALDH1A1SMN1; SMN2GLAMAPTKMT2A | |
| SCHEMBL2926247 | 0.80 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPTKMT2AMEN1QPCT | |
| Hydrochloric Acid SCHEMBL5718428 | 0.80 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2GLAMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL5718455 | 0.79 | MAOA (0.43) | ALDH1A1SMN1; SMN2GLAMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL5474632 | 0.79 | NPC1 (0.44) | SMN1; SMN2MAPTKMT2AMEN1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0928289-B1 | NOVEL CATIONIC OXIDATION BASES, THEIR USE FOR OXIDATION DYEING OF KERATIN FIBRES, DYEING COMPOSITIONS AND DYEING METHODS | OREAL (FR) | 2004-09-29 | — | — | EP | disclosed |
| EP-1018333-A2 | Use of cationic monobenzene nitroanilines for dyeing keratin fibres , compositions and dyeing process | L'OREAL (FR) | 2000-07-12 | — | — | EP | disclosed |
| EP-0928289-A1 | NOVEL CATIONIC OXIDATION BASES, THEIR USE FOR OXIDATION DYEING OF KERATIN FIBRES, DYEING COMPOSITIONS AND DYEING METHODS | L'OREAL (FR) | 1999-07-14 | — | — | EP | disclosed |
| WO-1999003836-A1 | NOVEL CATIONIC OXIDATION BASES, THEIR USE FOR OXIDATION DYEING OF KERATIN FIBRES, DYEING COMPOSITIONS AND DYEING METHODS | L'OREAL (FR) | 1999-01-28 | — | — | WO | disclosed |