Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.42 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | BRD2 | P25440 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6778755 | 0.98 | DHFR (0.45) | DHFRKDM4CFYNHDAC2HSD17B1 | |
| SCHEMBL6574523 | 0.86 | HDAC2 (0.51) | DHFRFYNHDAC2BAZ2BBAZ2A | |
| Hydrochloric Acid SCHEMBL6574159 | 0.84 | HDAC2 (0.50) | DHFRFYNHDAC2BAZ2BBAZ2A | |
| SCHEMBL6011749 | 0.83 | HDAC2 (0.48) | DHFRFYNHDAC2BAZ2BBAZ2A | |
| Hydrochloric Acid SCHEMBL6011524 | 0.81 | HDAC2 (0.47) | DHFRFYNHDAC2BAZ2BBAZ2A | |
| SCHEMBL3786454 | 0.81 | KDM4C (0.50) | DHFRKDM4CFYNHDAC2 | |
| SCHEMBL24454658 | 0.80 | ALDH1A1 (0.50) | DHFRHDAC2BAZ2BBAZ2ABRD4 | |
| SCHEMBL3786043 | 0.80 | FYN (0.57) | DHFRFYNHDAC2MCL1BRD4 | |
| SCHEMBL3784572 | 0.79 | MCL1 (0.51) | HSD17B1HSD17B2MCL1PDE10AMAP4K4 | |
| SCHEMBL3786461 | 0.78 | HDAC2 (0.56) | DHFRFYNHDAC2BRD4BRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208077-B1 | 2-HYDROXY-5-AMINO-BIPHENYL-DERIVATIVES AND OXIDATIVE HAIR COLOURING AGENTS CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2004-04-21 | — | — | EP | disclosed |