Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | DHFR | P00374 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.43 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | BRD2 | P25440 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.41 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.41 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6574159 | 0.98 | HDAC2 (0.50) | HDAC2DHFRPGRFYNBAZ2B | |
| SCHEMBL3785416 | 0.87 | FYN (0.45) | HDAC2DHFRPGRFYNALDH1A1 | |
| SCHEMBL6011749 | 0.87 | HDAC2 (0.48) | HDAC2DHFRPGRFYNBAZ2B | |
| SCHEMBL6573414 | 0.86 | DHFR (0.46) | HDAC2DHFRFYNBAZ2BBAZ2A | |
| Hydrochloric Acid SCHEMBL6011524 | 0.86 | HDAC2 (0.47) | HDAC2DHFRFYNBAZ2BBAZ2A | |
| SCHEMBL6572577 | 0.85 | KMO (0.53) | MAP4K4AKR1C3AKR1C2 | |
| Hydrochloric Acid SCHEMBL6778755 | 0.84 | DHFR (0.45) | HDAC2DHFRFYNBAZ2BBAZ2A | |
| SCHEMBL3790225 | 0.83 | HDAC2 (0.54) | HDAC2DHFRPGRBAZ2BBAZ2A | |
| SCHEMBL3786454 | 0.82 | KDM4C (0.50) | HDAC2DHFRFYNALDH1A1SYK | |
| SCHEMBL6571330 | 0.81 | MAPT (0.49) | HDAC2CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | claimed |
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | disclosed |