Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28944858 | 0.79 | MEN1 (0.37) | MEN1KMT2ASIGMAR1CCR5DRD2 | |
| SCHEMBL27393257 | 0.79 | SIGMAR1 (0.52) | MEN1KMT2ASIGMAR1CCR5DRD2 | |
| SCHEMBL2435647 | 0.77 | DPP4 (0.49) | CYP1A2CYP3A4CYP2D6CYP2C19DPP4 | |
| SCHEMBL2799626 | 0.76 | DRD2 (0.45) | SIGMAR1DRD2DPP4KCNA3 | |
| SCHEMBL8127083 | 0.76 | DPP4 (0.45) | SIGMAR1CYP1A2CYP2D6TSHRDPP4 | |
| SCHEMBL519227 | 0.76 | DPP4 (0.45) | DPP4 | |
| SCHEMBL9677809 | 0.73 | MAPT (0.44) | SIGMAR1 | |
| SCHEMBL3406346 | 0.72 | MAPT (0.46) | SIGMAR1CCR5TP53MDM2POLB | |
| SCHEMBL5426458 | 0.72 | SIGMAR1 (0.52) | SIGMAR1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL19002393 | 0.71 | SIGMAR1 (0.48) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409457-A1 | METHOD FOR PREPARING 4-METHYLAMINO-4-PHENYLPIPERIDINE | Sanofi-Aventis (FR) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003008381-A1 | METHOD FOR PREPARING 4-METHYLAMINO-4-PHENYLPIPERIDINE | SANOFI-SYNTHELABO (FR) | 2003-01-30 | — | — | WO | disclosed |