Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11148022 | 0.90 | NAAA (0.47) | SIGMAR1 | |
| SCHEMBL11147376 | 0.85 | NAAA (0.51) | SIGMAR1 | |
| SCHEMBL5426458 | 0.83 | SIGMAR1 (0.52) | SIGMAR1 | |
| SCHEMBL19002393 | 0.82 | SIGMAR1 (0.48) | MAPTSIGMAR1 | |
| SCHEMBL15709181 | 0.82 | SIGMAR1 (0.55) | SIGMAR1 | |
| SCHEMBL11147047 | 0.81 | ESR1 (0.36) | SIGMAR1 | |
| SCHEMBL11147084 | 0.81 | GAA (0.46) | SIGMAR1CTSLCTSBCTSK | |
| SCHEMBL11150214 | 0.81 | DPP4 (0.41) | MAPTSIGMAR1 | |
| SCHEMBL11145753 | 0.81 | CYP19A1 (0.47) | SIGMAR1 | |
| SCHEMBL19049578 | 0.80 | SIGMAR1 (0.44) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0373542-B1 | IMIDAZOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1992-06-17 | — | — | EP | disclosed |
| US-4996219-A | Antibody inhibitors | BOEHRINGER MANNHEIM GMBH (DE) | 1991-02-26 | — | — | US | disclosed |
| EP-0373542-A1 | Imidazoline derivatives, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1990-06-20 | — | — | EP | disclosed |
| US-4410532-A | N-Substituted aziridine-2-carboxylic acid derivatives and their immuno-stimulation compositions and methods | BOEHRINGER MANNHEIM GMBH (DE) | 1983-10-18 | — | — | US | disclosed |
| US-4409236-A | N-Substituted aziridine-2-carboxylic acid derivatives and immuno-stimulation composition and method | BOEHRINGER MANNHEIM GMBH (DE) | 1983-10-11 | — | — | US | disclosed |
| US-4321194-A | N-Substituted aziridine-2-carboxylic acid derivatives for immuno stimulation | BOEHRINGER MANNHEIM GMBH (DE) | 1982-03-23 | — | — | US | disclosed |