Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | TLR4 | O00206 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.49 |
| ▸ | RELA | Q04206 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 10/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 10/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 10/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 10/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 10/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 10/20 | 0.49 |
| ▸ | GRIN3A | Q8TCU5 | 10/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | FURIN | P09958 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7266109 | 0.98 | TLR4 (0.58) | MAPTGAAALDH1A1TLR4NPC1 | |
| SCHEMBL6574017 | 0.84 | TLR4 (0.52) | MAPTGAAALDH1A1TLR4GRIN2D | |
| SCHEMBL6573468 | 0.77 | GRIN2D (0.59) | MAPTGAAALDH1A1TLR4NPC1 | |
| SCHEMBL6573896 | 0.77 | MAPT (0.49) | MAPTGAAALDH1A1TLR4SMN1; SMN2 | |
| SCHEMBL28482894 | 0.76 | GRIN2D (0.67) | MAPTTLR4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10061889 | 0.74 | CA2 (0.55) | MAPTGAAALDH1A1NPC1RAB9A | |
| Water SCHEMBL6576235 | 0.73 | MAPT (0.97) | MAPTGAAALDH1A1NPC1RAB9A | |
| SCHEMBL6576397 | 0.71 | MAPT (0.48) | MAPTGAAALDH1A1TLR4NPC1 | |
| SCHEMBL6573971 | 0.71 | TLR4 (0.40) | MAPTGAAALDH1A1TLR4SMN1; SMN2 | |
| SCHEMBL6573504 | 0.71 | HTR1A (0.55) | MAPTGAAALDH1A1TLR4GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1120405-B1 | Oxidation bases with a guanidine chain, process for their preparation, their use for oxidation dyeing of keratinous fibers, dyeing compositions and dyeing processes | OREAL (FR) | 2004-10-27 | — | — | EP | claimed |
| US-20010034913-A1 | Novel oxidation bases containing a guanidine chain, process for preparing them, their use for the oxidation dyeing of keratin fibers, dye compositions and dyeing processes | L'OREAL S.A. (FR) | 2001-11-01 | — | — | US | claimed |
| EP-1120405-A2 | Oxidation bases with a guanidine chain, process for their preparation, their use for oxidation dyeing of keratinous fibers, dyeing compositions and dyeing processes | L'OREAL (FR) | 2001-08-01 | — | — | EP | claimed |
| EP-1120405-B1 | Oxidation bases with a guanidine chain, process for their preparation, their use for oxidation dyeing of keratinous fibers, dyeing compositions and dyeing processes | OREAL (FR) | 2004-10-27 | — | — | EP | disclosed |
| US-6652600-B2 | Oxidation color dye | L'OREAL S.A. (FR) | 2003-11-25 | — | — | US | disclosed |
| US-20010034913-A1 | Novel oxidation bases containing a guanidine chain, process for preparing them, their use for the oxidation dyeing of keratin fibers, dye compositions and dyeing processes | L'OREAL S.A. (FR) | 2001-11-01 | — | — | US | disclosed |
| EP-1120405-A2 | Oxidation bases with a guanidine chain, process for their preparation, their use for oxidation dyeing of keratinous fibers, dyeing compositions and dyeing processes | L'OREAL (FR) | 2001-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010034913-A1 | Novel oxidation bases containing a guanidine chain, process for preparing them, their use for the oxidation dyeing of keratin fibers, dye compositions and dyeing processes | KRT18, OGG1, UNG | MAPT 1802/4885GAA 2127/4885ALDH1A1 785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.