Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | DDX3X | O00571 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30335 | 0.80 | NPC1 (0.49) | GPR35NPC1KCNMA1GAAPOLB | |
| SCHEMBL70533 | 0.80 | GPR35 (0.75) | GPR35LMNATDP1ALDH1A1S100A4 | |
| SCHEMBL7568232 | 0.79 | GPR35 (0.53) | GPR35NPC1GAAPOLBMAPT | |
| SCHEMBL7616287 | 0.78 | TSHR (0.42) | GPR35NPC1KCNMA1GAAPOLB | |
| SCHEMBL18037665 | 0.76 | GPR35 (0.50) | GPR35NPC1KCNMA1GAAPOLB | |
| SCHEMBL8749191 | 0.76 | GPR35 (0.50) | GPR35GAAPOLBMAPTTDP1 | |
| SCHEMBL9370714 | 0.75 | GPR35 (0.49) | GPR35NPC1KCNMA1GAAPOLB | |
| SCHEMBL4363348 | 0.75 | GPR35 (0.60) | GPR35GAAMAPTTDP1ALDH1A1 | |
| SCHEMBL8026294 | 0.73 | DDX3X (0.63) | GAAMAPTDDX3XALDH1A1MEN1 | |
| SCHEMBL16979 | 0.72 | GPR35 (1.00) | GPR35KCNMA1TDP1ALDH1A1S100A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040237383-A1 | Combustion modifiers for water-blended fuels | LUBRIZOL CORPORATION, THE | 2004-12-02 | — | — | US | disclosed |
| EP-1408788-A1 | COMBUSTION MODIFIERS FOR WATER-BLENDED FUELS | THE LUBRIZOL CORPORATION (US) | 2004-04-21 | — | — | EP | disclosed |
| WO-2002068334-A1 | COMBUSTION MODIFIERS FOR WATER-BLENDED FUELS | THE LUBRIZOL CORPORATION (US) | 2002-09-06 | — | — | WO | disclosed |