SCHEMBL6573636

SCHEMBL6573636

Nc1ccc(N(CCO)CCO)cc1-c1cccc(C=O)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 1/20 0.37
TRIM33 Q9UPN9 1/20 0.37
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
KMT2A Q03164 3/20 0.33
MAPT P10636 2/20 0.33
MEN1 O00255 2/20 0.33
DYRK1A Q13627 2/20 0.33
DYRK2 Q92630 2/20 0.33
DYRK1B Q9Y463 2/20 0.33
AXL P30530 1/20 0.32
UNG P13051 1/20 0.32
NAT1 P18440 2/20 0.32
NPY5R Q15761 1/20 0.32
ALDH1A1 P00352 3/20 0.32
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
BRD4 O60885 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6572756 0.87 ALDH1A1 (0.40) KMT2AMAPTMEN1ALDH1A1TSHR
SCHEMBL6570954 0.84 CA12 (0.34) TRIM24TRIM33CA12CA1CA2
SCHEMBL6570998 0.82 MAPT (0.38) KMT2AMAPTMEN1ALDH1A1TSHR
SCHEMBL6571445 0.82 KMT2A (0.43) KMT2AMAPTMEN1ALDH1A1TSHR
SCHEMBL6571458 0.81 CYP3A4 (0.38) CA12CA1CA2CA9KMT2A
SCHEMBL6571005 0.81 TAAR1 (0.39) KMT2AMAPTMEN1DYRK1ATDP1
SCHEMBL6571939 0.80 STK4 (0.45) KMT2AMAPTMEN1GAAPKM
SCHEMBL6571701 0.80 MAPT (0.38) KMT2AMAPTMEN1DYRK1ADYRK1B
SCHEMBL6573422 0.80 HRH3 (0.42) KMT2AMAPTMEN1ALDH1A1GAA
SCHEMBL6573465 0.80 KMO (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1051143-B1 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES WELLA AG (DE) 2004-07-21 EP claimed
EP-1051143-B1 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES WELLA AG (DE) 2004-07-21 EP disclosed
US-6500213-B1 Oxidizing hair coloring agents containing 2,5-diamino-1-phenylbenzene derivatives and novel 2,5-diamino-1-phenylbenzene derivatives WELLA AKTIENGESELLSCHAFT (DE) 2002-12-31 US disclosed
EP-1051143-A2 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES Wella Aktiengesellschaft (DE) 2000-11-15 EP disclosed
WO-1999059527-A2 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES WELLA AKTIENGESELLSCHAFT (DE) 1999-11-25 WO disclosed