Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Xanthene SCHEMBL27518873 | 0.80 | MAOA (0.71) | MAOAMAOBHSD17B3NOTUMGAA | |
| Xanthene SCHEMBL11805046 | 0.80 | MAOA (0.71) | MAOAMAOBHSD17B3NOTUMGAA | |
| SCHEMBL1128333 | 0.74 | MAOA (0.46) | MAOAMAOBHSD17B3GAASMN1; SMN2 | |
| SCHEMBL10845751 | 0.74 | MAOA (0.55) | MAOAMAOBACSL1KDM4ENPC1 | |
| SCHEMBL9058487 | 0.73 | MAOA (0.44) | MAOAMAOBHSD17B3GAASMN1; SMN2 | |
| SCHEMBL8470353 | 0.73 | MAOA (0.65) | MAOAMAOBHSD17B3GAASMN1; SMN2 | |
| Xanthene SCHEMBL30838605 | 0.72 | MAOA (0.71) | MAOAMAOBGAASMN1; SMN2ACSL1 | |
| SCHEMBL10159163 | 0.72 | MAOA (0.58) | MAOAMAOBHSD17B3NOTUMGAA | |
| SCHEMBL11805061 | 0.72 | MAOA (0.47) | MAOAMAOBHSD17B3SMN1; SMN2ACSL1 | |
| Xanthene SCHEMBL29378346 | 0.71 | MAOA (1.00) | MAOAMAOBGAASMN1; SMN2ACSL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004123557-A | ARYLOXYMETHYLOXADIAZOLE DERIVATIVE | TAISHO PHARMACEUT CO LTD | 2004-04-22 | — | — | JP | disclosed |