Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.65 |
| ▸ | MAOB | P27338 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | ITGAL | P20701 | 1/20 | 0.35 |
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Xanthene SCHEMBL9339684 | 0.79 | MAOA (1.00) | MAOAMAOBGAANPSR1CYP1A2 | |
| Xanthene SCHEMBL4267 | 0.79 | MAOA (1.00) | MAOAMAOBGAANPSR1CYP1A2 | |
| Xanthene SCHEMBL27493963 | 0.79 | MAOA (1.00) | MAOAMAOBGAANPSR1CYP1A2 | |
| Xanthene SCHEMBL29378346 | 0.79 | MAOA (1.00) | MAOAMAOBGAANPSR1CYP1A2 | |
| Xanthene SCHEMBL30586075 | 0.79 | MAOA (1.00) | MAOAMAOBGAANPSR1CYP1A2 | |
| SCHEMBL737708 | 0.79 | MAOA (0.50) | MAOAMAOBGAANPSR1NPC1 | |
| Xanthene SCHEMBL27942350 | 0.78 | MAOA (0.85) | MAOAMAOBGAANPSR1CYP1A2 | |
| SCHEMBL985324 | 0.77 | MAOA (0.60) | MAOAMAOBGAANPSR1CYP1A2 | |
| Xanthene SCHEMBL23355281 | 0.77 | MAOA (0.94) | MAOAMAOBGAANPSR1CYP1A2 | |
| Xanthene SCHEMBL6192065 | 0.77 | MAOA (0.94) | MAOAMAOBGAANPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4122204-A | MITICIDES, INSECTICIDES | UNION CARBIDE CORPORATION (US) | 1978-10-24 | — | — | US | claimed |
| CN-117242060-A | Isoindolinone compounds | 蒙特罗萨医疗公司 | 2023-12-15 | — | — | CN | disclosed |
| EP-3580190-B1 | IN VIVO STABLE HG-197(M) COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF IN NUCLEAR MEDICAL DIAGNOSTICS AND ENDORADIONUCLIDE THERAPY (THERANOSTICS) | HELMHOLTZ ZENTRUM DRESDEN (DE) | 2021-08-04 | — | — | EP | disclosed |
| US-20210228748-A1 | IN VIVO STABLE HG-197(M) COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF IN NUCLEAR MEDICAL DIAGNOSTICS AND ENDORADIONUCLIDE THERAPY (THERANOSTICS) | HELMHOLTZ-ZENTRUM DRESDEN - ROSSENDORF E.V. (DE) | 2021-07-29 | — | — | US | disclosed |
| WO-2018146116-A1 | IN VIVO STABLE HG-197(M) COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF IN NUCLEAR MEDICAL DIAGNOSTICS AND ENDORADIONUCLIDE THERAPY (THERANOSTICS) | HELMHOLTZ-ZENTRUM DRESDEN - ROSSENDORF E.V. (DE) | 2018-08-16 | — | — | WO | disclosed |
| EP-0539803-B1 | Triazospirodecanone-methyl-chromans for the treatment of central nervous system illnesses | BAYER AG (DE) | 1999-01-07 | — | — | EP | disclosed |
| US-5843997-A | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1998-12-01 | — | — | US | disclosed |
| US-5576323-A | CENTRAL NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1996-11-19 | — | — | US | disclosed |
| EP-0658539-A1 | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1995-06-21 | — | — | EP | disclosed |
| EP-0539803-A1 | Triazospirodecanone-methyl-chromans for the treatment of central nervous system illnesses | BAYER AG (DE) | 1993-05-05 | — | — | EP | disclosed |
| US-4430341-A | INSECTICIDES, MITICIDES | UNION CARBIDE CORPORATION (US) | 1984-02-07 | — | — | US | disclosed |
| US-4201786-A | INSECTICIDES, MITICIDES | UNION CARBIDE CORPORATION (US) | 1980-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210228748-A1 | IN VIVO STABLE HG-197(M) COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF IN NUCLEAR MEDICAL DIAGNOSTICS AND ENDORADIONUCLIDE THERAPY (THERANOSTICS) | GDA, NPM1, GBA1 | MAOA 2180/4885MAOB 2797/4885GAA 47/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.