SCHEMBL6573680

SCHEMBL6573680

Cc1cn([C@H]2CC(OC(=O)OCC(C)c3ccccc3[N+](=O)[O-])[C@@H](CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.59

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
RNASE1 P07998 1/20 0.59
TK1 P04183 4/20 0.44
TK2 O00142 3/20 0.44
ALB P02768 1/20 0.43
PKM P14618 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6572381 1.00 RNASE1 (0.59) RNASE1TK1TK2ALBPKM
SCHEMBL7643615 0.93 RNASE1 (0.51) RNASE1TK1
SCHEMBL7644968 0.92 RNASE1 (0.59) RNASE1TK1TK2
SCHEMBL8719327 0.92 RNASE1 (0.59) RNASE1TK1TK2
SCHEMBL8722179 0.91 RNASE1 (0.58) RNASE1TK1TK2ALBPKM
SCHEMBL7644538 0.91 RNASE1 (0.58) RNASE1TK1TK2ALBPKM
SCHEMBL6834245 0.90 RNASE1 (0.53) RNASE1TK1TK2ALBPKM
SCHEMBL6834409 0.90 RNASE1 (0.53) RNASE1TK1TK2ALBPKM
SCHEMBL6834411 0.90 RNASE1 (0.53) RNASE1TK1TK2ALBPKM
SCHEMBL7053656 0.90 RNASE1 (0.53) RNASE1TK1TK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040203036-A1 Multimer polynucleotide synthesis CHEMOGENIX GMBH (DE) 2004-10-14 US disclosed
US-6756492-B1 Nucleoside derivatives with photo-unstable protective groups DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUND DES OFFENTLICHEN RECHTS (DE) 2004-06-29 US disclosed
EP-1409505-A1 MULTIMER POLYNUCLEOTIDE SYNTHESIS Chemogenix GmbH (DE) 2004-04-21 EP disclosed
WO-2003006476-A1 MULTIMER POLYNUCLEOTIDE SYNTHESIS CHEMOGENIX GMBH (DE) 2003-01-23 WO disclosed
US-5763599-A FOR LIGHT-CONTROLLED SYNTHESIS OF OLIGONUCLEOTIDES ON DNA CHIP Pfleiderer, Wolfgang (DE) 1998-06-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040203036-A1 Multimer polynucleotide synthesis NT5C3B, PCNA, POLL RNASE1 205/4885TK1 176/4885TK2 265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.