SCHEMBL7053656

SCHEMBL7053656

Cc1cn([C@H]2C[C@H](OC(=O)OCC(C)c3cc(Cl)ccc3[N+](=O)[O-])[C@@H](CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RNASE1 P07998 1/20 0.53
TK1 P04183 3/20 0.44
TK2 O00142 2/20 0.44
DTYMK P23919 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7566046 1.00 RNASE1 (0.53) RNASE1TK1TK2DTYMK
SCHEMBL6834133 0.94 RNASE1 (0.45) RNASE1TK1TK2
SCHEMBL6834411 0.92 RNASE1 (0.53) RNASE1TK1TK2
SCHEMBL6834409 0.92 RNASE1 (0.53) RNASE1TK1TK2
SCHEMBL6834245 0.92 RNASE1 (0.53) RNASE1TK1TK2
SCHEMBL6834246 0.92 RNASE1 (0.53) RNASE1TK1TK2
SCHEMBL6572381 0.90 RNASE1 (0.59) RNASE1TK1TK2
SCHEMBL6573680 0.90 RNASE1 (0.59) RNASE1TK1TK2
SCHEMBL13666504 0.86 POLB (0.45)
SCHEMBL6835955 0.86 POLB (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1224198-B1 NUCLEOSIDE DERIVATIVES WITH PHOTOLABILE PROTECTING GROUPS NIGU CHEMIE GMBH (DE) 2003-04-23 EP disclosed
US-20020146737-A1 Nucleoside derivatives with photolabile protective groups NIGU CHEMIE GMBH (DE) 2002-10-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020146737-A1 Nucleoside derivatives with photolabile protective groups XRN2, XPA, NSUN2 RNASE1 339/4885TK1 210/4885TK2 550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.