Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CETP | P11597 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6576055 | 0.96 | LMNA (0.48) | TSHRFOLH1KDM4ELMNAALDH1A1 | |
| SCHEMBL6575683 | 0.90 | TSHR (0.51) | TSHRFOLH1CETPHTTHDAC3 | |
| SCHEMBL9939056 | 0.85 | MAPT (0.51) | TSHRFOLH1ALDH1A1CETPHTT | |
| SCHEMBL5472579 | 0.81 | TSHR (0.55) | TSHRFOLH1ALDH1A1CETPHTT | |
| SCHEMBL23067163 | 0.80 | TSHR (0.44) | TSHRFOLH1ALDH1A1CETPMAPK1 | |
| SCHEMBL2365443 | 0.78 | TSHR (0.57) | TSHRCETP | |
| SCHEMBL26699446 | 0.77 | ALDH1A1 (0.46) | TSHRKDM4ELMNAALDH1A1CETP | |
| SCHEMBL4109675 | 0.77 | LMNA (0.54) | TSHRKDM4ELMNAALDH1A1HTT | |
| SCHEMBL5424748 | 0.75 | TSHR (0.50) | TSHRCETP | |
| SCHEMBL4948490 | 0.75 | CYP3A4 (0.59) | TSHRALDH1A1CETPMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1427710-A2 | METHOD FOR THE PRODUCTION OF CNA | Nanogen Recognomics GmbH (DE) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003016561-A2 | METHOD FOR THE PRODUCTION OF CNA | NANOGEN RECOGNOMICS GMBH (DE) | 2003-02-27 | — | — | WO | disclosed |