SCHEMBL6574093

SCHEMBL6574093

COCCN(CCOC)c1ccc(N)c(-c2c(C)cc(C)cc2C)c1

nearest known ligand 0.47

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CRHR1 P34998 17/20 0.47
S100B P04271 1/20 0.40
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6572437 0.83 S100B (0.41) CRHR1S100BMAPK1
SCHEMBL6570859 0.82 S100B (0.37) CRHR1S100BMAPK1
SCHEMBL6572636 0.81 CRHR1 (0.34) CRHR1S100B
SCHEMBL6572502 0.81 S100B (0.40) CRHR1S100B
SCHEMBL17550792 0.81 S100B (0.61) CRHR1S100BMAPK1
SCHEMBL6573326 0.80 ALDH1A1 (0.35) CRHR1S100BMAPK1
SCHEMBL6572821 0.78 ALDH1A1 (0.37) CRHR1S100B
SCHEMBL6572811 0.78 CRHR1 (0.37) CRHR1S100B
SCHEMBL7691074 0.77 S100B (0.34) CRHR1S100B
SCHEMBL6573501 0.77 S100B (0.35) S100B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1051143-B1 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES WELLA AG (DE) 2004-07-21 EP claimed
EP-1051143-B1 OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES WELLA AG (DE) 2004-07-21 EP disclosed
US-6500213-B1 Oxidizing hair coloring agents containing 2,5-diamino-1-phenylbenzene derivatives and novel 2,5-diamino-1-phenylbenzene derivatives WELLA AKTIENGESELLSCHAFT (DE) 2002-12-31 US disclosed