Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FCGR3B | O75015 | 1/20 | 0.33 |
| ▸ | FCGR1A | P12314 | 1/20 | 0.33 |
| ▸ | FCGR2A | P12318 | 1/20 | 0.33 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6572072 | 0.92 | FCGR3B (0.34) | FCGR3BFCGR1AFCGR2ARPS6KA2ALDH1A1 | |
| SCHEMBL6570894 | 0.86 | ALDH1A1 (0.36) | FCGR3BFCGR1AFCGR2ARPS6KA2ALDH1A1 | |
| SCHEMBL6570680 | 0.82 | AR (0.31) | — | |
| SCHEMBL6572599 | 0.81 | KMT2A (0.36) | FCGR3BFCGR1AFCGR2AALDH1A1KDM4E | |
| SCHEMBL6572949 | 0.81 | FCGR3B (0.38) | FCGR3BFCGR1AFCGR2AALDH1A1KDM4E | |
| SCHEMBL6574122 | 0.81 | HTR6 (0.37) | FCGR3BFCGR1AFCGR2AKDM4EGLA | |
| SCHEMBL6572408 | 0.78 | PDE10A (0.40) | FCGR3BFCGR1AFCGR2AALDH1A1KDM4E | |
| SCHEMBL6573252 | 0.78 | PRSS1 (0.36) | FCGR3BFCGR1AFCGR2AALDH1A1KDM4E | |
| SCHEMBL6570745 | 0.78 | BRD4 (0.39) | FCGR3BFCGR1AFCGR2AALDH1A1KDM4E | |
| SCHEMBL5373965 | 0.78 | KDM4E (0.36) | FCGR3BFCGR1AFCGR2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | claimed |
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | disclosed |
| US-6500213-B1 | Oxidizing hair coloring agents containing 2,5-diamino-1-phenylbenzene derivatives and novel 2,5-diamino-1-phenylbenzene derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2002-12-31 | — | — | US | disclosed |
| EP-1051143-A2 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | Wella Aktiengesellschaft (DE) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999059527-A2 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 1999-11-25 | — | — | WO | disclosed |