Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | METAP2 | P50579 | 5/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.39 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6764627 | 0.78 | F2 (0.60) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6574437 | 0.78 | ALDH1A1 (0.44) | HTTALDH1A1GAAF2PRSS1 | |
| SCHEMBL6574363 | 0.73 | MCL1 (0.47) | HTTALDH1A1GAAF2PRSS1 | |
| SCHEMBL6765941 | 0.67 | F2 (0.59) | HTTALDH1A1GAAF2PRSS1 | |
| SCHEMBL17331322 | 0.64 | CYP2C9 (0.60) | HTTALDH1A1GAAKMT2AMETAP2 | |
| SCHEMBL5326622 | 0.64 | METAP2 (0.61) | HTTALDH1A1GAAKMT2AMETAP2 | |
| SCHEMBL17331324 | 0.63 | CYP2C9 (0.80) | HTTALDH1A1GAAKMT2ATSHR | |
| SCHEMBL5728635 | 0.62 | ABAT (0.47) | ALDH1A1GAAKMT2AALOX15HSD17B10 | |
| SCHEMBL5822638 | 0.62 | FFAR4 (0.72) | HTTALDH1A1GAAKMT2AMETAP2 | |
| Hydrochloric Acid SCHEMBL11624632 | 0.62 | GAA (0.42) | ALDH1A1GAAPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414790-A1 | SUBSTITUTED N-ACYL ANILINE DERIVATIVES, PRODUCTION AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2004-05-06 | — | — | EP | disclosed |
| WO-2003000653-A1 | SUBSTITUTED N-ACYL ANILINE DERIVATIVES, PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO.KG (DE) | 2003-01-03 | — | — | WO | disclosed |