Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | METAP2 | P50579 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6574434 | 0.78 | HTT (0.45) | ALDH1A1GAAHTTF2PRSS1 | |
| SCHEMBL6764627 | 0.78 | F2 (0.60) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6574363 | 0.72 | MCL1 (0.47) | ALDH1A1GAAHTTF2PRSS1 | |
| SCHEMBL6765941 | 0.66 | F2 (0.59) | ALDH1A1GAAHTTF2PRSS1 | |
| SCHEMBL17331322 | 0.63 | CYP2C9 (0.60) | ALDH1A1GAAHTTKMT2AMETAP2 | |
| SCHEMBL5326622 | 0.63 | METAP2 (0.61) | ALDH1A1GAAHTTKMT2AMETAP2 | |
| SCHEMBL5326630 | 0.62 | ACLY (0.72) | ALDH1A1GAAKMT2AMETAP2TSHR | |
| SCHEMBL5822638 | 0.62 | FFAR4 (0.72) | ALDH1A1GAAHTTKMT2AMETAP2 | |
| SCHEMBL2616424 | 0.62 | METAP2 (0.63) | ALDH1A1GAAHTTKMT2AMETAP2 | |
| SCHEMBL7589780 | 0.61 | ALDH1A1 (0.69) | ALDH1A1GAAHTTKMT2AMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414790-A1 | SUBSTITUTED N-ACYL ANILINE DERIVATIVES, PRODUCTION AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2004-05-06 | — | — | EP | disclosed |
| WO-2003000653-A1 | SUBSTITUTED N-ACYL ANILINE DERIVATIVES, PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO.KG (DE) | 2003-01-03 | — | — | WO | disclosed |