Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 16/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6576874 | 0.91 | ADORA3 (0.51) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL6573093 | 0.88 | ADORA1 (0.48) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL6576751 | 0.86 | ADORA3 (0.51) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL6574496 | 0.85 | ADORA3 (0.44) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL6576860 | 0.85 | ADORA3 (0.44) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL6574597 | 0.84 | ADORA3 (0.46) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL6574690 | 0.84 | ADORA1 (0.49) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL6572752 | 0.80 | ADORA2A (0.51) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL6572760 | 0.77 | ADORA3 (0.47) | ADORA3ADORA1ADORA2AADORA2BNT5E | |
| SCHEMBL6575072 | 0.77 | ADORA3 (0.54) | ADORA3ADORA1ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090019-B1 | ADENOSINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2004-09-29 | — | — | EP | claimed |