Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 13/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6576751 | 0.95 | ADORA3 (0.51) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL6574494 | 0.91 | ADORA3 (0.41) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL6573093 | 0.90 | ADORA1 (0.48) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL6574690 | 0.85 | ADORA1 (0.49) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL6575079 | 0.84 | ADORA3 (0.54) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL6575072 | 0.84 | ADORA3 (0.54) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL6575216 | 0.84 | ADORA3 (0.59) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL6798263 | 0.80 | ADORA2A (0.66) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL6576785 | 0.80 | ADORA2A (0.66) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL6574581 | 0.80 | ADORA3 (0.54) | ADORA3ADORA2AADORA2BADORA1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090019-B1 | ADENOSINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2004-09-29 | — | — | EP | claimed |