Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 3/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.38 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL634456 | 0.86 | BACE1 (0.54) | BACE1AKR1C2AKR1C1PTPN1ALOX5 | |
| SCHEMBL6572245 | 0.84 | BACE1 (0.54) | BACE1AKR1C2AKR1C1PTPN1ALOX5 | |
| SCHEMBL27907556 | 0.80 | HSD17B10 (0.41) | BACE1ALDH1A1HSD17B10PTGDR2SMARCA2 | |
| SCHEMBL29973116 | 0.80 | HSD17B10 (0.41) | RPS6KA3BACE1ALDH1A1HSD17B10PTGDR2 | |
| SCHEMBL4447987 | 0.80 | HSD17B10 (0.41) | RPS6KA3BACE1ALDH1A1HSD17B10PTGDR2 | |
| SCHEMBL6573889 | 0.77 | THRB (0.56) | BACE1AKR1C2AKR1C1PTPN1ALOX5 | |
| SCHEMBL30286418 | 0.77 | RPS6KA3 (0.46) | RPS6KA3BACE1AKR1C2AKR1C1PTPN1 | |
| SCHEMBL6572603 | 0.77 | ESR2 (0.48) | RPS6KA3BACE1AKR1C2AKR1C1PTPN1 | |
| SCHEMBL1759524 | 0.76 | RPS6KA3 (0.49) | RPS6KA3BACE1AKR1C2AKR1C1PTPN1 | |
| SCHEMBL14832983 | 0.76 | BACE1 (0.48) | RPS6KA3BACE1AKR1C2AKR1C1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208077-B1 | 2-HYDROXY-5-AMINO-BIPHENYL-DERIVATIVES AND OXIDATIVE HAIR COLOURING AGENTS CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2004-04-21 | — | — | EP | disclosed |