Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL634456 | 0.89 | BACE1 (0.54) | BACE1ALOX5HSD17B10ALDH1A1HPGD | |
| SCHEMBL6574554 | 0.84 | RPS6KA3 (0.46) | BACE1ALOX5HSD17B10ALDH1A1HPGD | |
| SCHEMBL6572603 | 0.80 | ESR2 (0.48) | BACE1ALOX5HSD17B10ALDH1A1HPGD | |
| SCHEMBL6573889 | 0.80 | THRB (0.56) | BACE1ALOX5HSD17B10ALDH1A1HPGD | |
| SCHEMBL6574657 | 0.80 | BACE1 (0.47) | BACE1HSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL6576074 | 0.79 | SMN1; SMN2 (0.42) | HSD17B10ALDH1A1HPGDBCL2L1MEN1 | |
| SCHEMBL3788108 | 0.78 | ALOX5 (0.61) | BACE1ALOX5HSD17B10ALDH1A1HPGD | |
| SCHEMBL11674213 | 0.77 | PTPN1 (0.69) | HSD17B10ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL30230742 | 0.77 | BACE1 (0.62) | BACE1ALOX5HSD17B10ALDH1A1HPGD | |
| SCHEMBL900806 | 0.77 | BACE1 (0.62) | BACE1ALOX5HSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208077-B1 | 2-HYDROXY-5-AMINO-BIPHENYL-DERIVATIVES AND OXIDATIVE HAIR COLOURING AGENTS CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2004-04-21 | — | — | EP | disclosed |