Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.38 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.38 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4447987 | 1.00 | HSD17B10 (0.41) | HSD17B10ALDH1A1MAOATAAR1TDP1 | |
| SCHEMBL24254882 | 0.84 | HSD17B10 (0.50) | HSD17B10ALDH1A1MAOATAAR1TDP1 | |
| SCHEMBL2834500 | 0.83 | IKBKB (0.49) | HSD17B10ALDH1A1MAOATAAR1TDP1 | |
| SCHEMBL28106449 | 0.83 | METAP2 (0.42) | HSD17B10ALDH1A1MAOATAAR1SMARCA2 | |
| SCHEMBL27907556 | 0.83 | HSD17B10 (0.41) | HSD17B10ALDH1A1MAOATAAR1TDP1 | |
| SCHEMBL6574554 | 0.80 | RPS6KA3 (0.46) | HSD17B10ALDH1A1MAOASMARCA2SMARCA4 | |
| SCHEMBL18582910 | 0.80 | NUDT1 (0.45) | HSD17B10ALDH1A1SMARCA2SMARCA4PBRM1 | |
| SCHEMBL28466437 | 0.79 | HSD17B10 (0.41) | HSD17B10ALDH1A1MAOATAAR1TDP1 | |
| SCHEMBL2912921 | 0.79 | SMARCA2 (0.42) | HSD17B10ALDH1A1MAOATAAR1TDP1 | |
| SCHEMBL30413647 | 0.79 | HSD17B10 (0.41) | HSD17B10ALDH1A1MAOATAAR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081199-A2 | LIPOXYGENASE INHIBITORS | SRI International (US) | 2022-11-02 | — | — | EP | disclosed |