Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6572387 | 0.86 | MEN1 (0.40) | MAPTALDH1A1SMN1; SMN2GCGRMAOA | |
| SCHEMBL6574010 | 0.80 | GAA (0.35) | MAPTALDH1A1SMN1; SMN2GCGRGAA | |
| SCHEMBL6573483 | 0.79 | KDM4E (0.50) | MAPTALDH1A1SMN1; SMN2GAAKMT2A | |
| Hydrochloric Acid SCHEMBL7266101 | 0.78 | KDM4E (0.49) | MAPTALDH1A1SMN1; SMN2GAAKMT2A | |
| SCHEMBL6573896 | 0.75 | MAPT (0.49) | MAPTALDH1A1SMN1; SMN2GAAKDM4E | |
| SCHEMBL6576274 | 0.74 | MAOA (0.44) | MAPTALDH1A1SMN1; SMN2MAOAGAA | |
| SCHEMBL6573944 | 0.74 | LMNA (0.32) | MAPTALDH1A1SMN1; SMN2GAAKMT2A | |
| SCHEMBL6573458 | 0.71 | KDM4E (0.46) | MAPTALDH1A1SMN1; SMN2MAOAGAA | |
| SCHEMBL4093134 | 0.69 | MAPT (0.78) | MAPTALDH1A1SMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL7747538 | 0.68 | MAOA (0.71) | MAPTALDH1A1SMN1; SMN2MAOAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1120405-B1 | Oxidation bases with a guanidine chain, process for their preparation, their use for oxidation dyeing of keratinous fibers, dyeing compositions and dyeing processes | OREAL (FR) | 2004-10-27 | — | — | EP | claimed |
| US-20010034913-A1 | Novel oxidation bases containing a guanidine chain, process for preparing them, their use for the oxidation dyeing of keratin fibers, dye compositions and dyeing processes | L'OREAL S.A. (FR) | 2001-11-01 | — | — | US | claimed |
| EP-1120405-A2 | Oxidation bases with a guanidine chain, process for their preparation, their use for oxidation dyeing of keratinous fibers, dyeing compositions and dyeing processes | L'OREAL (FR) | 2001-08-01 | — | — | EP | claimed |
| EP-1120405-B1 | Oxidation bases with a guanidine chain, process for their preparation, their use for oxidation dyeing of keratinous fibers, dyeing compositions and dyeing processes | OREAL (FR) | 2004-10-27 | — | — | EP | disclosed |
| US-6652600-B2 | Oxidation color dye | L'OREAL S.A. (FR) | 2003-11-25 | — | — | US | disclosed |
| US-20010034913-A1 | Novel oxidation bases containing a guanidine chain, process for preparing them, their use for the oxidation dyeing of keratin fibers, dye compositions and dyeing processes | L'OREAL S.A. (FR) | 2001-11-01 | — | — | US | disclosed |
| EP-1120405-A2 | Oxidation bases with a guanidine chain, process for their preparation, their use for oxidation dyeing of keratinous fibers, dyeing compositions and dyeing processes | L'OREAL (FR) | 2001-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010034913-A1 | Novel oxidation bases containing a guanidine chain, process for preparing them, their use for the oxidation dyeing of keratin fibers, dye compositions and dyeing processes | KRT18, OGG1, UNG | MAPT 1802/4885ALDH1A1 785/4885SMN1; SMN2 3509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.