Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 2/20 | 0.38 |
| ▸ | WEE1 | P30291 | 3/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6572605 | 0.86 | APP (0.43) | NR3C1APPMAPTGAASMN1; SMN2 | |
| SCHEMBL6571324 | 0.84 | PRKCI (0.37) | TNIKAPPMAPTGAAMEN1 | |
| SCHEMBL6572108 | 0.77 | NR3C1 (0.48) | NR3C1APPMAPTGAASMN1; SMN2 | |
| SCHEMBL6572302 | 0.76 | PRKCI (0.39) | MAPTGAASMN1; SMN2MEN1NPC1 | |
| SCHEMBL6572330 | 0.75 | HTR7 (0.45) | APPMAPTGAAALDH1A1MAPK1 | |
| SCHEMBL6571007 | 0.72 | PDE10A (0.41) | TNIKGAAKMT2AALDH1A1TSHR | |
| SCHEMBL6574045 | 0.72 | EGFR (0.49) | NR3C1MAOBMAPTGAAMEN1 | |
| SCHEMBL6571037 | 0.71 | TSHR (0.40) | NR3C1MAPTGAASMN1; SMN2MEN1 | |
| SCHEMBL6572102 | 0.71 | ALDH1A1 (0.48) | MAOBAPPMAPTSMN1; SMN2MEN1 | |
| SCHEMBL8107397 | 0.71 | NR3C1 (0.37) | NR3C1WEE1CHEK1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | disclosed |