Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 8/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | NT5E | P21589 | 2/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6574661 | 0.94 | ADORA1 (0.48) | ADORA1ADORA2AADORA3HTR2CTMIGD3 | |
| Formic Acid SCHEMBL6574660 | 0.90 | ADORA2A (0.53) | ADORA1ADORA2AADORA3HTR2CTMIGD3 | |
| SCHEMBL6576736 | 0.85 | ADORA1 (0.47) | ADORA1ADORA2AADORA3HTR2CTMIGD3 | |
| SCHEMBL6574869 | 0.83 | ADORA1 (0.47) | ADORA1ADORA2AADORA3HTR2CTMIGD3 | |
| SCHEMBL6839089 | 0.82 | ADORA1 (0.46) | ADORA1ADORA2AADORA3HTR2CTMIGD3 | |
| SCHEMBL8090571 | 0.82 | ADORA3 (0.58) | ADORA1ADORA2AADORA3HTR2CTMIGD3 | |
| SCHEMBL3914182 | 0.82 | ADORA3 (0.58) | ADORA1ADORA2AADORA3HTR2CTMIGD3 | |
| SCHEMBL3914192 | 0.82 | ADORA3 (0.58) | ADORA1ADORA2AADORA3HTR2CTMIGD3 | |
| SCHEMBL6838972 | 0.82 | ADORA2A (0.45) | ADORA1ADORA2AADORA3ADORA2B | |
| SCHEMBL6839268 | 0.81 | ADORA2A (0.40) | ADORA1ADORA2AADORA3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090019-B1 | ADENOSINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2004-09-29 | — | — | EP | disclosed |
| EP-1447407-A1 | Adenosine derivatives | GLAXO GROUP LIMITED (GB) | 2004-08-18 | — | — | EP | disclosed |