Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11596188 | 0.87 | — | — | |
| SCHEMBL2023113 | 0.83 | DNM1 (0.52) | DNM1CA1CA2HTT | |
| SCHEMBL10780852 | 0.81 | DNM1 (0.61) | DNM1CA1CA2HTT | |
| SCHEMBL11597777 | 0.79 | DNM1 (0.65) | DNM1CA1CA2HTT | |
| SCHEMBL6575134 | 0.78 | CA1 (0.33) | DNM1CA1CA2 | |
| SCHEMBL16281634 | 0.78 | TSHR (0.34) | DNM1CA1CA2HTT | |
| SCHEMBL10430663 | 0.77 | CA1 (0.31) | DNM1CA1CA2 | |
| SCHEMBL289118 | 0.75 | — | — | |
| SCHEMBL11381692 | 0.75 | CA1 (0.33) | CA1CA2 | |
| SCHEMBL4425572 | 0.75 | CA1 (0.33) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110317212-B | Synthesis of polycyclic carbamoylpyridone compounds | 吉利德科学公司 | 2022-10-21 | — | — | CN | claimed |
| EP-3527573-B9 | SYNTHESIS OF POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS | GILEAD SCIENCES INC (US) | 2022-07-06 | — | — | EP | claimed |
| US-10975096-B2 | Synthesis of polycyclic-carbamoylpyridone compounds | GILEAD SCIENCES, INC. (US) | 2021-04-13 | — | — | US | claimed |
| EP-3783001-A1 | SYNTHESIS OF POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS | Gilead Sciences, Inc. (US) | 2021-02-24 | — | — | EP | claimed |
| EP-3527573-B1 | SYNTHESIS OF POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS | GILEAD SCIENCES INC (US) | 2020-08-12 | — | — | EP | claimed |
| US-20200223866-A1 | SYNTHESIS OF POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS | GILEAD SCIENCES, INC. | 2020-07-16 | — | — | US | claimed |
| EP-3527573-A1 | SYNTHESIS OF POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS | Gilead Sciences, Inc. (US) | 2019-08-21 | — | — | EP | claimed |
| EP-3148674-B1 | ABSORBENT SOLUTION CONTAINING A MIXTURE OF 1,2-BIS-(2-DIMETHYLAMINOETHOXY)-ETHANE AND 2-[2-(2- DIMETHYLAMINOETHOXY)-ETHOXY]-ETHANOL, AND METHOD FOR ELIMINATING ACID COMPOUNDS FROM A GAS EFFLUENT | IFP ENERGIES NOW (FR) | 2018-07-11 | — | — | EP | claimed |
| US-9962645-B2 | Absorbent solution containing a mixture of 1,2-bis-(2-dimethylaminoethoxy)-ethane and of 2-[2-(2-dimethylaminoethoxy)-ethoxy]-ethanol, and method of removing acid compounds from a gaseous effluent | IFP Energies Nouvelles (FR) | 2018-05-08 | — | — | US | claimed |
| US-20170197176-A1 | ABSORBENT SOLUTION CONTAINING A MIXTURE OF 1,2-BIS-(2-DIMETHYLAMINOETHOXY)-ETHANE AND OF 2-[2-(2-DIMETHYLAMINOETHOXY)-ETHOXY]-ETHANOL, AND METHOD OF REMOVING ACID COMPOUNDS FROM A GASEOUS EFFLUENT | IFP Energies Nouvelles (FR) | 2017-07-13 | — | — | US | claimed |
| CN-110317212-B | Synthesis of polycyclic carbamoylpyridone compounds | 吉利德科学公司 | 2022-10-21 | — | — | CN | disclosed |
| EP-3527573-B9 | SYNTHESIS OF POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS | GILEAD SCIENCES INC (US) | 2022-07-06 | — | — | EP | disclosed |
| CN-114394983-A | Synthesis of polycyclic carbamoylpyridone compounds | 吉利德科学公司 | 2022-04-26 | — | — | CN | disclosed |
| US-10975096-B2 | Synthesis of polycyclic-carbamoylpyridone compounds | GILEAD SCIENCES, INC. (US) | 2021-04-13 | — | — | US | disclosed |
| EP-3783001-A1 | SYNTHESIS OF POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS | Gilead Sciences, Inc. (US) | 2021-02-24 | — | — | EP | disclosed |
| US-4792630-A | REACTING HALOGENOACETALDEHYDE DIALKYLACETAL WITH AMMONIA OR ALKYLAMINE | NIPPON GOSEI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-12-20 | — | — | US | disclosed |
| US-4769480-A | Benzylamine derivative | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1988-09-06 | — | — | US | disclosed |
| EP-0214051-A2 | Benzylamine derivative | MITSUBISHI KASEI CORPORATION (JP) | 1987-03-11 | — | — | EP | disclosed |
| US-4118216-A | HERBICIDES | VELSICOL CHEMICAL COMPANY (US) | 1978-10-03 | — | — | US | disclosed |
| US-4097491-A | HERBICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1978-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200223866-A1 | SYNTHESIS OF POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS | CPS1, SDHA, DHPS | DNM1 1895/4885CA1 764/4885CA2 880/4885 |
| US-10975096-B2 | Synthesis of polycyclic-carbamoylpyridone compounds | CPS1, SDHA, DHPS | DNM1 1895/4885CA1 764/4885CA2 880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.