Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.43 |
| ▸ | GUSB | P08236 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1028616 | 0.81 | XDH (0.38) | SLC6A4 | |
| SCHEMBL30892212 | 0.81 | XDH (0.38) | SLC6A4 | |
| SCHEMBL3197383 | 0.77 | CDK4 (0.49) | — | |
| SCHEMBL20595125 | 0.77 | IMPDH2 (0.30) | — | |
| SCHEMBL2111365 | 0.74 | ATM (0.44) | SLC6A4SLC6A2SLC6A3BCHE | |
| SCHEMBL29414051 | 0.74 | ATM (0.44) | SLC6A4SLC6A2SLC6A3BCHE | |
| SCHEMBL30182153 | 0.74 | HTR1D (0.42) | IDO1SLC6A4SLC6A3 | |
| SCHEMBL16924038 | 0.73 | ALDH1A1 (0.34) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL14895853 | 0.73 | CYP2A6 (0.35) | — | |
| SCHEMBL931715 | 0.73 | CYP2A6 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116693538-A | Pyrazolopyrimidine derivative, and preparation method and application thereof | 成都苑东生物制药股份有限公司 | 2023-09-05 | — | — | CN | disclosed |
| US-8378104-B2 | 7-aminofuropyridine derivatives | OSI Pharmaceuticals, LLC (US) | 2013-02-19 | — | — | US | disclosed |
| US-20120046267-A1 | 7-AMINOFUROPYRIDINE DERIVATIVES | OSI PHARMACEUTICALS, INC. | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046267-A1 | 7-AMINOFUROPYRIDINE DERIVATIVES | MAP3K5, STK17A, MAPKAPK5 | IDO1 1522/4885SLC6A4 3454/4885GUSB 4240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.