⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4137033 | 0.87 | PHF8 (0.38) | — | |
| SCHEMBL8156188 | 0.83 | SLC22A6 (0.58) | — | |
| SCHEMBL11250230 | 0.83 | LMNA (0.58) | — | |
| SCHEMBL11248102 | 0.81 | TSHR (0.60) | — | |
| SCHEMBL11247262 | 0.81 | TSHR (0.60) | — | |
| Succinic Acid SCHEMBL2220518 | 0.77 | — | — | |
| Succinic Acid SCHEMBL30548271 | 0.77 | LMNA (0.90) | — | |
| SCHEMBL17232594 | 0.75 | PHF8 (0.70) | — | |
| SCHEMBL264229 | 0.74 | — | — | |
| Succinic Acid SCHEMBL24696 | 0.73 | LMNA (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 322 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10414749-B2 | Process for preparing 3-[(S)-7-bromo-2-((2-oxopropyl)amino)-5-pyridin-2-yl-3H-1,4-benzodiazepin-3-yl]propionic acid methyl ester | PAION UK LIMITED (GB) | 2019-09-17 | — | — | US | claimed |
| EP-2006274-B1 | METHOD FOR PRODUCING 3,3,3-TRIFLUOROPROPIONIC ACID CHLORIDE | CENTRAL GLASS CO LTD (JP) | 2016-12-21 | — | — | EP | claimed |
| US-7754927-B2 | Method for producing 3,3,3-trifluoropropionyl chloride | CENTRAL GLASS COMPANY, LIMITED (JP) | 2010-07-13 | — | — | US | claimed |
| US-20100113834-A1 | chlorinating 3,3,3-trifluoropropionaldehyde with a radical initiator; also producing 3,3,3-trifluoropropionic acid by hydrolysis; useful as an intermediate of medicines and agricultural chemicals and a fluoropolymer | CENTRAL GLASS COMPANY LIMITED (JP) | 2010-05-06 | — | — | US | claimed |
| EP-2006274-A1 | METHOD FOR PRODUCING 3,3,3-TRIFLUOROPROPIONIC ACID CHLORIDE | Central Glass Co., Ltd. (JP) | 2008-12-24 | — | — | EP | claimed |
| US-5137981-A | Heat resistant rubber; esterification butadiene polymer using halogenated carboxy compound | BRIDGESTONE CORPORATION (JP) | 1992-08-11 | — | — | US | claimed |
| EP-0328291-B1 | HALOGENATED POLYBUTADIENE SERIES ELASTOMERS, METHOD OF PRODUCING THE SAME, AND RUBBER COMPOSITIONS FOR TIRES CONTAINING THE ELASTOMER | Bridgestone Corporation (JP) | 1992-04-29 | — | — | EP | claimed |
| EP-0328291-A1 | Halogenated polybutadiene series elastomers, method of producing the same, and rubber compositions for tires containing the elastomer | Bridgestone Corporation (JP) | 1989-08-16 | — | — | EP | claimed |
| US-4250063-A | COORDINATION CATALYST COMPRISING AN ORGANIC COMPLEX OF TUNGSTEN OR MOLYBDENUM, A TITANIUM TETRAHALIDE, AND AN N-HALO IMIDE, A SULFIDE, A SULFOXIDE, OR A PHOSPHINE; POLYALKENAMERS | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1981-02-10 | — | — | US | claimed |
| JP-2001433-A | — | — | None | — | — | JP | disclosed |
| JP-5286962-A | — | — | None | — | — | JP | disclosed |
| JP-8269052-A | — | — | None | — | — | JP | disclosed |
| JP-4139169-A | — | — | None | — | — | JP | disclosed |
| JP-4282362-A | — | — | None | — | — | JP | disclosed |
| EP-0047674-B1 | NOVEL PROCESS FOR PREPARING ISOINDOLIN DERIVATIVES | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1984-02-29 | — | — | EP | disclosed |
| US-4400520-A | Novel process for preparing isoindoline derivatives | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1983-08-23 | — | — | US | disclosed |
| EP-0047674-A1 | Novel process for preparing isoindolin derivatives | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1982-03-17 | — | — | EP | disclosed |
| US-4250063-A | COORDINATION CATALYST COMPRISING AN ORGANIC COMPLEX OF TUNGSTEN OR MOLYBDENUM, A TITANIUM TETRAHALIDE, AND AN N-HALO IMIDE, A SULFIDE, A SULFOXIDE, OR A PHOSPHINE; POLYALKENAMERS | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1981-02-10 | — | — | US | disclosed |
| JP-S5520727-A | PREPARATION OF 2-ANILINOPHENYL ACETATE | MITSUI TOATSU CHEM INC | 1980-02-14 | — | — | JP | disclosed |
| US-4117036-A | ANAEROBIC CURABILITY, SEALANTS | BRIDGESTONE TIRE COMPANY LIMITED (JP) | 1978-09-26 | — | — | US | disclosed |