SCHEMBL6575559

SCHEMBL6575559

CC(C)(C)[Si](C)(C)O[C@H]1C[C@H](OCc2ccccc2)C[C@@H](O)[C@@H]1CO

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PDE4D Q08499 1/20 0.39
OPRM1 P35372 2/20 0.33
OPRL1 P41146 2/20 0.33
SLC6A2 P23975 1/20 0.33
CTSL P07711 1/20 0.33
CTSB P07858 1/20 0.33
CTSK P43235 1/20 0.33
SLC18A3 Q16572 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7493619 0.89 PDE4D (0.34) PDE4DOPRM1OPRL1CTSLCTSB
SCHEMBL4899890 0.89 PDE4D (0.34) PDE4DOPRM1OPRL1CTSLCTSB
SCHEMBL14107808 0.86 CTSL (0.37) PDE4DOPRM1OPRL1SLC6A2CTSL
SCHEMBL4893196 0.86 CTSL (0.37) PDE4DOPRM1OPRL1SLC6A2CTSL
SCHEMBL4895151 0.80 CTSL (0.36) OPRM1OPRL1CTSLCTSBCTSK
SCHEMBL14107809 0.80 CTSL (0.36) OPRM1OPRL1CTSLCTSBCTSK
SCHEMBL21029509 0.79 CTSL (0.41) OPRM1OPRL1CTSLCTSBCTSK
SCHEMBL22906947 0.79 CTSL (0.41) OPRM1OPRL1CTSLCTSBCTSK
SCHEMBL21028938 0.79 CTSL (0.41) OPRM1OPRL1CTSLCTSBCTSK
SCHEMBL4899900 0.77 GABRA5 (0.32) PDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1210347-B1 CARBOCYCLIC NUCLEOSIDES AND PROCESS FOR OBTAINING SUCH STICHTING REGA V Z W (BE) 2004-06-23 EP disclosed