Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 2/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14107808 | 1.00 | CTSL (0.37) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL14107809 | 0.86 | CTSL (0.36) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL4895151 | 0.86 | CTSL (0.36) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL6575559 | 0.86 | PDE4D (0.39) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL22906947 | 0.85 | CTSL (0.41) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL21028938 | 0.85 | CTSL (0.41) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL21029509 | 0.85 | CTSL (0.41) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL7493619 | 0.84 | PDE4D (0.34) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL4899890 | 0.84 | PDE4D (0.34) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL14107863 | 0.81 | OPRM1 (0.39) | CTSLCTSBCTSKOPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402688-B2 | 2,2-Di-substituted 1alpha,25-dihydroxy-19-norvitamin D derivative | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-07-22 | — | — | US | disclosed |
| US-20060160779-A1 | 2,2-Di-substituted 1alpha,25-dihydroxy-19-norvitamin d derivative | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2006-07-20 | — | — | US | disclosed |
| EP-1559708-A1 | 2,2-DI-SUBSTITUTED 1a,25-DIHYDROXY-19-NORVITAMIN D DERIVATIVE | Shimizu, Masato (JP) | 2005-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160779-A1 | 2,2-Di-substituted 1alpha,25-dihydroxy-19-norvitamin d derivative | CYP24A1, CYP2R1, VDR | CTSL 2998/4885CTSB 3354/4885CTSK 3561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.