SCHEMBL6575560

SCHEMBL6575560

O=P(O)(O)OSc1nc(Cl)c(Cl)cc1Cl

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34
MMP3 P08254 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPT P10636 1/20 0.30
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30
ALOX12 P18054 1/20 0.30
MAPK1 P28482 1/20 0.30
ATM Q13315 1/20 0.30
HSD17B10 Q99714 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27542334 0.77 MMP1 (0.37) MMP1MMP2MMP3TDP1MEN1
SCHEMBL16506502 0.69 TDP1 (0.54) MMP1MMP2MMP3TDP1MEN1
SCHEMBL11110277 0.69 TDP1 (0.42) TDP1MEN1KMT2AALDH1A1CYP3A4
SCHEMBL11110306 0.66 TDP1 (0.47) TDP1MEN1KMT2AALDH1A1CYP3A4
Hydrochloric Acid SCHEMBL11736764 0.66 CYP3A4 (0.33) ALDH1A1CYP3A4HSD17B10
SCHEMBL990015 0.63 TDP1 (0.51) MMP1MMP2MMP3TDP1MEN1
SCHEMBL2366051 0.62 TDP1 (0.41) TDP1MEN1KMT2AALDH1A1CYP3A4
SCHEMBL5912465 0.61 TDP1 (0.35) TDP1MEN1KMT2AALDH1A1CYP3A4
Phosphoric Acid SCHEMBL27955583 0.61 KMT2A (0.49) MMP1MMP2MMP3TDP1KMT2A
SCHEMBL9416947 0.59 SRC (0.46) ALDH1A1MAPTALOX15TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0851008-B1 Paints inhibiting the chitin synthesis in arthropods, for the control of pests and allergens MATEO HERRERO MARIA PILAR (ES) 2004-05-06 EP claimed
EP-0065851-B1 INSECTICIDAL SYNERGISTIC MIXTURES OF O,O-DIETHYL O-(3,5,6-TRICHLORO-2-PYRIDINYL)PHOSPHOROTHIOATE AND O,O-DIMETHYL-S-(N-METHYLCARBAMOYLMETHYL)PHOSPHOROTHIOATE AND METHOD OF KILLING AND CONTROLLING INSECTS THE DOW CHEMICAL COMPANY (US) 1986-06-25 EP claimed
US-5874025-A Timber preservative containing a copper compound BAYER AKTIENGESELLSCHAFT (DE) 1999-02-23 US disclosed