Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.46 |
| ▸ | KLK1 | P06870 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6575632 | 1.00 | KLKB1 (0.46) | KLKB1KLK1PTPN1FOLH1MME | |
| SCHEMBL6573593 | 0.88 | PTPN1 (0.46) | KLKB1KLK1PTPN1FOLH1MME | |
| SCHEMBL6573589 | 0.88 | PTPN1 (0.46) | KLKB1KLK1PTPN1FOLH1MME | |
| SCHEMBL6572832 | 0.86 | SRC (0.55) | PTPN1FOLH1 | |
| SCHEMBL6572828 | 0.86 | SRC (0.55) | PTPN1FOLH1 | |
| SCHEMBL6572632 | 0.86 | ITGB3 (0.48) | KLKB1KLK1PTPN1FOLH1PTPN22 | |
| SCHEMBL6572635 | 0.86 | ITGB3 (0.48) | KLKB1KLK1PTPN1FOLH1PTPN22 | |
| SCHEMBL6575538 | 0.83 | SRD5A2 (0.45) | PTPN1FOLH1 | |
| SCHEMBL6571434 | 0.83 | PTPN1 (0.62) | PTPN1 | |
| SCHEMBL6572344 | 0.83 | PTPN1 (0.62) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019364-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-19 | — | — | EP | claimed |
| WO-1999011606-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | PHARMACIA & UPJOHN COMPANY (US) | 1999-03-11 | — | — | WO | claimed |
| EP-1019364-B1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | BIOVITRUM AB (SE) | 2004-06-09 | — | — | EP | disclosed |
| US-6410585-B1 | THERAPY FOR NON-INSULIN DEPEND DIABETES | BIOVITRUM AB (SE) | 2002-06-25 | — | — | US | disclosed |
| US-6353023-B1 | AROMATIC COMPOUNDS WITH AMIDE GROUPS | PHARMACIA & UPJOHN COMPANY | 2002-03-05 | — | — | US | disclosed |
| EP-1019364-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999011606-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | PHARMACIA & UPJOHN COMPANY (US) | 1999-03-11 | — | — | WO | disclosed |