SCHEMBL6575865

SCHEMBL6575865

CCCCCCC(=O)OCC(C)(C)C(OC(=O)CCCCCC)C(C)C

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.54
ALDH1A1 P00352 1/20 0.53
MAPT P10636 2/20 0.50
PRKCA P17252 1/20 0.49
PRKCE Q02156 1/20 0.49
PRKCQ Q04759 1/20 0.49
PRKCD Q05655 1/20 0.49
DGKA P23743 1/20 0.49
MAPK1 P28482 1/20 0.47
PAM P19021 2/20 0.45
KDM4E B2RXH2 1/20 0.44
DUSP3 P51452 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
ENPP2 Q13822 1/20 0.44
LPAR1 Q92633 1/20 0.44
LPAR3 Q9UBY5 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6536003 1.00 LMNA (0.54) LMNAALDH1A1MAPTPRKCAPRKCE
SCHEMBL21636778 0.88 LMNA (0.37) LMNAALDH1A1MAPTPRKCAPRKCE
SCHEMBL9718333 0.83 LMNA (0.39) LMNAALDH1A1MAPTPRKCAPRKCE
SCHEMBL9323852 0.79 ALDH1A1 (0.33) ALDH1A1
SCHEMBL29868194 0.79 LMNA (0.53) LMNAALDH1A1MAPTPRKCAPRKCE
SCHEMBL4445942 0.79 ALDH1A1 (0.34) LMNAALDH1A1MAPT
SCHEMBL11291928 0.78 TSHR (0.35) LMNAALDH1A1MAPTPRKCAPRKCE
SCHEMBL11291925 0.78 TSHR (0.35) LMNAALDH1A1MAPTMAPK1PAM
SCHEMBL11656123 0.76 LMNA (0.43) LMNAALDH1A1MAPTPRKCAPRKCE
SCHEMBL17694525 0.76 MAPT (0.47) LMNAALDH1A1MAPTPRKCAPRKCE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0897416-B1 REFRIGERATION OILS COMPRISING ESTERS OF HINDERED ALCOHOLS EXXONMOBIL OIL CORP (US) 2004-05-06 EP disclosed
EP-0897416-A4 REFRIGERATION OILS COMPRISING ESTERS OF HINDERED ALCOHOLS MOBIL OIL CORP (US) 1999-10-20 EP disclosed
EP-0897416-A1 REFRIGERATION OILS COMPRISING ESTERS OF HINDERED ALCOHOLS MOBIL OIL CORPORATION (US) 1999-02-24 EP disclosed
US-5705086-A HYDROFLUOROCARBONS MOBIL OIL CORPORATION (US) 1998-01-06 US disclosed
WO-1997039079-A1 REFRIGERATION OILS COMPRISING ESTERS OF HINDERED ALCOHOLS MOBIL OIL CORPORATION (US) 1997-10-23 WO disclosed