Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | DGKA | P23743 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11291925 | 0.94 | TSHR (0.35) | LMNAALDH1A1MAPTMAPK1 | |
| SCHEMBL4445941 | 0.89 | LMNA (0.36) | LMNAALDH1A1 | |
| SCHEMBL11289512 | 0.88 | KDM6B (0.33) | — | |
| SCHEMBL29796685 | 0.84 | ALDH1A1 (0.33) | ALDH1A1MAPTPOLB | |
| SCHEMBL43993 | 0.84 | ALDH1A1 (0.33) | ALDH1A1MAPTPOLB | |
| SCHEMBL6575865 | 0.83 | LMNA (0.54) | LMNAALDH1A1MAPTMAPK1PRKCA | |
| SCHEMBL6536003 | 0.83 | LMNA (0.54) | LMNAALDH1A1MAPTMAPK1PRKCA | |
| SCHEMBL11291928 | 0.82 | TSHR (0.35) | LMNAALDH1A1MAPTPRKCAPRKCE | |
| SCHEMBL11315933 | 0.81 | TSHR (0.35) | ALDH1A1MAPTPOLB | |
| SCHEMBL30038608 | 0.81 | ALDH1A1 (0.32) | ALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358181-A2 | Polyvinyl chloride blends having improved physical properties | The Geon Company (US) | 1990-03-14 | — | — | EP | claimed |
| EP-0473915-A1 | Improved barrier PVC resins, compounds and articles derived therefrom | THE B.F. GOODRICH COMPANY (US) | 1992-03-11 | — | — | EP | disclosed |
| US-4348455-A | BY COATING WITH AN ALKALI METAL DIALKYL SULFOSUCCINATE | MOBIL OIL CORPORATION (US) | 1982-09-07 | — | — | US | disclosed |