Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.40 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5687750 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1HSD17B10HPGDBCL2L1 | |
| SCHEMBL6572245 | 0.79 | BACE1 (0.54) | SMN1; SMN2ALDH1A1HSD17B10HPGDBCL2L1 | |
| SCHEMBL6573481 | 0.78 | PDE10A (0.52) | SMN1; SMN2ALDH1A1HSD17B10HPGDBCL2L1 | |
| SCHEMBL19486098 | 0.76 | BRD4 (0.46) | SMN1; SMN2ALDH1A1HSD17B10HPGDBCL2L1 | |
| SCHEMBL6573277 | 0.75 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1HSD17B10HPGDBCL2L1 | |
| SCHEMBL5684574 | 0.75 | PLAU (0.47) | SMN1; SMN2ALDH1A1HSD17B10HPGDTDP1 | |
| Hydroxyamine SCHEMBL28237907 | 0.74 | ALDH1A1 (0.60) | SMN1; SMN2ALDH1A1HSD17B10HPGDBCL2L1 | |
| SCHEMBL28574 | 0.74 | ALDH1A1 (0.67) | SMN1; SMN2ALDH1A1HSD17B10HPGDBCL2L1 | |
| SCHEMBL30442890 | 0.74 | ALDH1A1 (0.67) | SMN1; SMN2ALDH1A1HSD17B10HPGDBCL2L1 | |
| SCHEMBL29623192 | 0.74 | ALDH1A1 (0.67) | SMN1; SMN2ALDH1A1HSD17B10HPGDBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208077-B1 | 2-HYDROXY-5-AMINO-BIPHENYL-DERIVATIVES AND OXIDATIVE HAIR COLOURING AGENTS CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2004-04-21 | — | — | EP | disclosed |