⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6248584 | 0.68 | — | — | |
| SCHEMBL6246758 | 0.66 | — | — | |
| SCHEMBL4377359 | 0.60 | LMNA (0.33) | — | |
| SCHEMBL24749379 | 0.58 | GABRR1 (0.34) | — | |
| SCHEMBL7905164 | 0.57 | ALDH1A1 (0.45) | — | |
| SCHEMBL1184526 | 0.57 | — | — | |
| SCHEMBL152172 | 0.57 | — | — | |
| SCHEMBL24456546 | 0.57 | — | — | |
| SCHEMBL10956840 | 0.57 | — | — | |
| SCHEMBL23435207 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1280760-B1 | NOVEL SPIRO[2.4]HEPTANE AMINO CARBOXY COMPOUNDS AND DERIVATIVES THEREOF | CURRY KENNETH (CA) | 2004-04-28 | — | — | EP | disclosed |
| US-20040077599-A1 | Novel spiro[2.4]heptane amino carboxy compounds and derivatives thereof | CURRY KENNETH (CA) | 2004-04-22 | — | — | US | disclosed |
| EP-1280760-A1 | NOVEL SPIRO[2.4]HEPTANE AMINO CARBOXY COMPOUNDS AND DERIVATIVES THEREOF | Curry, Kenneth (CA) | 2003-02-05 | — | — | EP | disclosed |
| WO-2001085669-A1 | NOVEL SPIRO[2.4]HEPTANE AMINO CARBOXY COMPOUNDS AND DERIVATIVES THEREOF | CURRY KENNETH (CA) | 2001-11-15 | — | — | WO | disclosed |