Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.56 |
| ▸ | TYR | P14679 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3972328 | 0.81 | TAAR1 (0.54) | CHRNA7TYRMEN1CYP3A4MAPT | |
| SCHEMBL2767004 | 0.81 | CHRNA7 (0.53) | CHRNA7TYRMEN1TP53CYP3A4 | |
| SCHEMBL27814767 | 0.79 | TYR (0.55) | CHRNA7TYRMEN1TP53CYP3A4 | |
| SCHEMBL2766520 | 0.79 | CHRNA7 (0.51) | CHRNA7TYRMEN1TP53CYP3A4 | |
| SCHEMBL1121847 | 0.78 | IDO1 (0.50) | — | |
| SCHEMBL2765682 | 0.78 | IDO1 (0.50) | — | |
| SCHEMBL29447941 | 0.78 | IDO1 (0.50) | — | |
| SCHEMBL2298211 | 0.77 | PDPK1 (0.45) | — | |
| SCHEMBL28796070 | 0.76 | CYP4F2 (0.38) | CHRNA7HTTTDP1 | |
| SCHEMBL27716488 | 0.76 | TYR (0.72) | CHRNA7TYRMEN1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1002791-B1 | AMINOETHYLPHENOXYACETIC ACID DERIVATIVES AND DRUGS FOR PAIN REMISSION AND CALCULI REMOVAL PROMOTION IN URINARY LITHIASIS | KISSEI PHARMACEUTICAL (JP) | 2004-10-20 | — | — | EP | disclosed |
| US-6399660-B1 | AMINOETHYLPHENOXYACETIC ACID COMPOUND | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2002-06-04 | — | — | US | disclosed |
| EP-1002791-A1 | AMINOETHYLPHENOXYACETIC ACID DERIVATIVES AND DRUGS FOR PAIN REMISSION AND CALCULI REMOVAL PROMOTION IN URINARY LITHIASIS | Kissei Pharmaceutical Co., Ltd. (JP) | 2000-05-24 | — | — | EP | disclosed |