Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 9/20 | 0.47 |
| ▸ | THRB | P10828 | 8/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6578828 | 0.81 | KMT2A (0.45) | MAOATSHRALDH1A1LMNA | |
| SCHEMBL6579115 | 0.77 | THRA (0.42) | THRATHRBMAOBPLA2G4BTSHR | |
| SCHEMBL6581974 | 0.76 | PPARA (0.47) | THRATHRB | |
| SCHEMBL6581909 | 0.76 | PPARA (0.47) | THRATHRB | |
| SCHEMBL6579060 | 0.76 | MAPT (0.41) | THRATHRBTSHRALDH1A1LMNA | |
| SCHEMBL9015804 | 0.76 | THRA (0.53) | THRATHRBPTPN11PLA2G4BTSHR | |
| SCHEMBL6576677 | 0.76 | CYP1A2 (0.43) | TSHRALDH1A1LMNA | |
| SCHEMBL27733999 | 0.74 | CA12 (0.61) | THRATHRBMAOBTSHRALDH1A1 | |
| SCHEMBL6581270 | 0.74 | KMT2A (0.42) | MAOATSHRALDH1A1LMNA | |
| SCHEMBL8185682 | 0.73 | HSD17B10 (0.57) | THRATHRBPTPN11PLA2G4BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6271416-B1 | O-(HYDROCARBONOXYACETAMIDO)BENZOIC ACID DERIVATIVES AS INTERMEDIATES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6136822-A | ETHER, HYDROXY QUINOLINONE COMPOUNDS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0927718-A1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-07-07 | — | — | EP | disclosed |