Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | THRA | P10827 | 5/20 | 0.51 |
| ▸ | THRB | P10828 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22749335 | 0.86 | ALDH1A1 (0.58) | HSD17B10ALDH1A1KDM4ELMNANPC1 | |
| SCHEMBL27733999 | 0.85 | CA12 (0.61) | HSD17B10ALDH1A1POLBLMNATHRA | |
| SCHEMBL8183565 | 0.85 | PTPN11 (0.61) | TSHRPTPN11TP53PLA2G4B | |
| SCHEMBL4251894 | 0.83 | ALDH1A1 (0.55) | HSD17B10ALDH1A1KDM4ETSHR | |
| SCHEMBL7773557 | 0.83 | PTPN11 (0.59) | TSHRPTPN11TP53PLA2G4B | |
| SCHEMBL29045460 | 0.82 | ALDH1A1 (0.52) | HSD17B10ALDH1A1KDM4EPOLBLMNA | |
| SCHEMBL8185676 | 0.82 | ALDH1A1 (0.46) | HSD17B10ALDH1A1KDM4EPOLBLMNA | |
| SCHEMBL8185679 | 0.82 | ALDH1A1 (0.46) | HSD17B10ALDH1A1KDM4EPOLBLMNA | |
| SCHEMBL23045006 | 0.82 | HSD17B10 (0.48) | HSD17B10ALDH1A1KDM4ELMNANPC1 | |
| SCHEMBL9015804 | 0.81 | THRA (0.53) | HSD17B10ALDH1A1LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143208-A | Optical element and compounds used in its manufacture | ROLIC AG (CH) | 2000-11-07 | — | — | US | disclosed |
| US-5335303-A | Quasi-phased matched optical waveguide frequency conversion element having a ferroelectric liquid crystalline material exhibiting a periodic structure | HOFFMANN-LA ROCHE INC. (US) | 1994-08-02 | — | — | US | disclosed |