Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TOP1 | P11387 | 2/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | CTSV | O60911 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 3/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6577098 | 1.00 | MAPT (0.38) | MAPTTOP1S100A4ERN1CTSV | |
| SCHEMBL6579512 | 0.91 | TOP1 (0.40) | MAPTTOP1S100A4ERN1CTSV | |
| SCHEMBL6579521 | 0.91 | TOP1 (0.40) | MAPTTOP1S100A4ERN1CTSV | |
| SCHEMBL6582135 | 0.76 | CNR1 (0.39) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL6582132 | 0.76 | CNR1 (0.39) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL7988582 | 0.74 | ALDH1A1 (0.45) | MAPTTOP1S100A4ALDH1A1HTT | |
| SCHEMBL6578992 | 0.73 | MAPT (0.49) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL6579909 | 0.71 | CYP1A2 (0.51) | MAPTHTTMEN1KMT2ALMNA | |
| SCHEMBL6582308 | 0.70 | MAPT (0.47) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL7988381 | 0.69 | HTT (0.42) | MAPTTOP1S100A4ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927718-B1 | Quinolinone derivative, method for preparing the same, and anti-allergic agent | DAINIPPON INK & CHEMICALS (JP) | 2004-02-25 | — | — | EP | disclosed |