Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1666508 | 0.79 | MEN1 (0.38) | PPARAALDH1A1MEN1LMNATHRB | |
| SCHEMBL2859889 | 0.78 | CYP1A2 (0.35) | PPARAFOLH1PPARGALDH1A1HTT | |
| SCHEMBL28224452 | 0.77 | BID (0.49) | PPARAFOLH1PTPN1PPARG | |
| SCHEMBL547665 | 0.74 | LMNA (0.50) | PTGDR2ALDH1A1MEN1LMNATHRB | |
| SCHEMBL28206869 | 0.73 | ERN1 (0.50) | PTPN1ALDH1A1MEN1THRBKMT2A | |
| Fluoride SCHEMBL14237094 | 0.72 | LMNA (0.48) | PTGDR2ALDH1A1MEN1LMNATHRB | |
| SCHEMBL2179847 | 0.72 | LIPG (0.42) | PPARAALDH1A1MEN1LMNATHRB | |
| SCHEMBL6704515 | 0.72 | PPARA (0.41) | PPARAALDH1A1HPGDCTSLCTSS | |
| SCHEMBL29953931 | 0.72 | ERN1 (0.52) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL1527632 | 0.72 | ERN1 (0.52) | MEN1LMNATHRBBLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456160-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003050067-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, SNC (FR) | 2003-06-19 | — | — | WO | disclosed |